Yes, this is possible. See cursor. Example (from that link). Basically you set cursor option for the series:

plotOptions: {
            series: {
                cursor: 'pointer',
                events: {
                    click: function() {
                        alert('You just clicked the graph');

If you want to make the whole chart clickable then you need to handle mouse hover/over. But then you may lose detail on where you are clicking (want to click series point but now you cant because you captured it on the "top" layer).

Related Query

More Query from same tag